Sunday, September 30, 2012

New Melanoma Treatment Might Delay Cancer Progression

Experimental drug combo postponed resistance to therapy by 4 months, study showed.

SATURDAY, Sept. 29 (HealthDay News) -- Researchers say they've discovered a two-drug combination that delays treatment resistance in patients with advanced melanoma.

By targeting different points in the same growth-factor pathway, the kinase inhibitor drugs dabrafenib and trametinib postponed the development of drug resistance in patients with BRAF-positive metastatic melanoma, the study authors said.

Melanoma is the most serious, and often deadly, form of skin cancer. In about half of patients with melanoma that has spread, tumor growth is caused by genetic mutations that keep the BRAF protein -- part of the MAPK cell growth pathway -- constantly activated. Drugs that inhibit BRAF activity can rapidly stop and reverse tumor growth in about 90 percent of patients. But the response is temporary in most cases, and tumor growth resumes in six or seven months, the researchers explained.

Previous research suggested that this drug resistance develops because the MAPK pathway gets turned back on through activation of MEK, another protein that is part off the MAPK pathway.

"We investigated this (drug) combination because of research we and others have conducted into the molecular underpinnings of resistance to BRAF inhibitor therapy," study lead author Dr. Keith Flaherty, of the Massachusetts General Hospital Cancer Center, said in a hospital news release.

The phase 1 and 2 study was sponsored by GlaxoSmithKline, which developed both drugs.

"We found that adding the MEK inhibitor trametinib to BRAF inhibitor dabrafenib clearly delays the emergence of resistance. In fact, the combination was at least twice as effective as BRAF inhibition alone," he said.

One expert agreed that the results were encouraging.

"This study addresses the problem of resistance to the mitogen-activated protein kinase [MAPK] pathway. This study combined dabrafenib [a selective BRAF inhibitor] and trametinib, [a selective MAPK kinase (MEK) inhibitor]. These drugs can be safely combined, and the survival was significantly improved without untoward side effects," said Dr. Michele Green, a dermatologist at Lenox Hill Hospital in New York City.

The study was conducted at 14 sites in the United States and Australia and included 162 patients who received different dose combinations of the drugs: two daily 150 milligram (mg) doses of dabrafenib plus one 2 mg dose of trametinib; the same dabrafenib dose with a 1 mg dose of trametinib; or treatment with dabrafenib alone.

Patients who received dabrafenib alone were able to receive the full-dose combination treatment if their cancer resumed progression.

Treatment with both combinations of dabrafenib and trametinib led to a four-month longer delay in drug resistance than treatment with dabrafenib alone. After one year of treatment, 41 percent of patients receiving the full-dose combination treatment had no progression of their melanoma, compared with 9 percent of those receiving dabrafenib alone.

Among patients receiving the combination treatment, the development of side effects such as skin rash and a less dangerous type of skin cancer called squamous cell carcinoma was similar to that typically seen in patients taking only one of the drugs.

The study was scheduled for presentation Saturday at the European Society for Medical Oncology meeting in Vienna and simultaneous publication in the New England Journal of Medicine.

The drug combination is now being tested in a larger phase 3 study, which is required for U.S. Food and Drug Administration approval.

More information

The American Cancer Society has more about melanoma.??External Links Disclaimer Logo

(SOURCE: Michele Green, M.D., dermatologist, Lenox Hill Hospital, New York City; Massachusetts General Hospital, news release, Sept. 29, 2012)

Copyright ? 2012 HealthDay. External Links Disclaimer Logo?All rights reserved.

HealthDayNews articles are derived from various sources and do not reflect federal policy. healthfinder.gov does not endorse opinions, products, or services that may appear in news stories. For more information on health topics in the news, visit Health News on healthfinder.gov.

Source: http://www.healthfinder.gov/news/newsstory.aspx?Docid=669108

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Military death toll in Afghanistan reaches 2,000

While the US prepares to withdraw most of its troops from Afghanistan by 2014, the number of military deaths in the country continues to rise. The toll is now at 2,000.

By Patrick Quinn,?Associated Press / September 30, 2012

US soldiers attend a ceremony marking the seventh anniversary of the Sept. 11 attacks, at the US Camp Phoenix in Kabul, Afghanistan in 2008. US military deaths in Afghanistan have surpassed 2,000, a grim reminder that a war which began nearly 11 years ago shows no signs of slowing down despite an American decision to begin the withdrawal of most of its combat forces.

Musadeq Sadeq/AP/File

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US military deaths in the Afghan war have reached 2,000, a cold reminder of the human cost of an 11-year-old conflict that now garners little public interest at home as the United States prepares to withdraw most of its combat forces by the end of 2014.

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The toll has climbed steadily in recent months with a spate of attacks by Afghan army and police ? supposed allies ? against American and NATO troops. That has raised troubling questions about whether countries in the U.S.-led coalition in?Afghanistan?will achieve their aim of helping the government in Kabul and its forces stand on their own after most foreign troops depart in little more than two years.

On Sunday, a US official confirmed the latest death, saying that an international service member killed in an apparent insider attack by Afghan forces in the east of the country late Saturday was American. A civilian contractor with NATO and at least two Afghan soldiers also died in the attack, according to a coalition statement and Afghan provincial officials. The U.S. official spoke on condition of anonymity because the nationality of those killed had not been formally released. Names of the dead are usually released after their families or next-of-kin are notified, a process that can take several days. The nationality of the civilian was also not disclosed.

In addition to the 2,000 Americans killed since the Afghan war began on Oct. 7, 2001, at least 1,190 more coalition troops from other countries have also died, according to iCasualties.org, an independent organization that tracks the deaths.

According to the?Afghanistan?index kept by the Washington-based research center Brookings Institution, about 40 percent of the American deaths were caused by improvised explosive devices. The majority of those were after 2009, when President Barack Obama ordered a surge that sent in 33,000 additional troops to combat heightened Taliban activity. The surge brought the total number of American troops to 101,000, the peak for the entire war.

According to Brookings, hostile fire was the second most common cause of death, accounting for nearly 31 percent of Americans killed.

Tracking deaths of Afghan civilians is much more difficult. According to the U.N., 13,431 civilians were killed in the Afghan conflict between 2007, when the U.N. began keeping statistics, and the end of August. Going back to the U.S.-led invasion in 2001, most estimates put the number of Afghan civilian deaths in the war at more than 20,000.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/NPNREXTw6AM/Military-death-toll-in-Afghanistan-reaches-2-000

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New US Jobs Report Alters Presidential Campaigns (Voice Of America)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/251951097?client_source=feed&format=rss

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Wonderful Advice To Help You With Self Improvement | Bob Spiro's ...

Personal development means working to improve awareness and build your identity. Self improvement usually focuses on increasing your self-awareness, expanding your knowledge, taking steps towards achieving personal goals and working on spiritual growth. This article touches on a lot of different ideas on how to work on self improvement. If you take it slowly you will know who you are.

Focus on making your time spent working as productive as possible. The simple trick is to take more breaks when you work. Although this may not seem to make sense, frequent breaks can give you time to relax and get re-energized, so that you will be more focused when you return to your work.

TIP! Becoming more healthy is an important part of developing personally. It takes motivation to maintain a healthy lifestyle, both through diet and exercise.

One way to improve yourself is to discover and emphasize your strengths, while minimizing your weaknesses. Determine what is important to you. Value your personal best and make that important to your life.

Taking occasional risks, on a small level, can help you lead a happier life! Many do not want to risk feeling like a failure, or feeling rejected, so they are often stuck in comfort zone that leaves them feeling unfulfilled. Taking risks shows courage, which is a component that can help you on the path of happiness.

We are all imperfect humans and we make mistakes in our choices every now and then, such as eating the wrong foods. Stress hurts your body as much as a large slice of high calorie pie, so take it all in stride.

TIP! Learn how to listen to others. This is particularly true when you are talking about self-development.

A precise goal, that is clear in definition, is needed for success with self improvement. Define a goal that can be measured. A specific goal will often achieve the desired results.

If you find that you are constantly having difficulty meeting your goals, take a step back to evaluate what?s going on. Check online and find others whom share similar goals with you and find out what they are doing compared to what you?re doing. You might find you are making simple mistakes such as not spending enough time or not getting the right information.

Try to get more organized. When you are organized, you will improve your confidence and feel accomplished in many different areas of your life. Additionally, it will remove the stress caused by living a disorganized life. Having everything in its rightful place will give you a sense of calm and ease.

TIP! Generally, if you are good to the people in your life, it will come back to you through good luck. Wish others well in life so you feel positive empowerment.

It?s a good personal guideline to treat everyone with respect even if they don?t necessarily have anything you might need from them. How you treat them reveals more about your own character, than it reveals about theirs.

Learn what others have done that has made them successful. The most obvious way to avoid pitfalls in both career and personal matters is to know what those pitfalls are and find out how other people avoided them. It is always beneficial to hear the stories about roads traveled by other individuals, especially very successful individuals.

The most important person to please is yourself; your self-esteem and happiness should come before anyone else?s opinion or desire. Think of yourself first, but don?t step on others just to get what you want. If you make sure that what you do is true to yourself and your ethics, you will be much happier with your self improvement path.

Praise others, flatter them, and show your appreciation. Being nice to others will help you learn to be nicer to yourself.

Do not over do it physically when trying to attain a goal. Although you should always try your best, you should also be aware of your limitations. You have to keep your body in mind when you are trying to accomplish something. Sacrificing your body to reach your goal is in fact contrary to the idea of improving yourself.

Knowing what you want out of life and how to get there are great tools for self improvement. Having long-term goals is great, because you could have a big change in your perspective.

TIP! Having written goals can help you experience more personal growth. One thing a lot of people lack and what you might want to write down is to have more confidence.

You should monitor your progress whenever you engage in any kind of personal development plan. This article has advice to help you know exactly what you must be doing. Write down the processes you use on a regular basis and record changes that occur

Bob Spiro

For MLM Pros Team Founder

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Source: http://www.empowernetwork.com/formlmpros/blog/wonderful-advice-to-help-you-with-self-improvement/

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Like, Share, and show your support for clean energy that is 500k times more effi...

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Friday, September 28, 2012

Occupy protester can't keep tweets from DA

6 hrs.

NEW YORK???An Occupy Wall Street protester has lost his latest bid to prevent the Manhattan district attorney's office from using his tweets against him, clearing the way for the judge overseeing the case to unseal the tweets and give them to prosecutors.

In a case that has drawn the attention of electronic privacy advocates, a New York judge denied a request from the protester, Malcolm Harris, to put the tweets on ice while his appeal is pending.

Harris, 23, was arrested along with hundreds of others during a mass march across the Brooklyn Bridge in October 2011 for obstructing vehicular traffic.

Prosecutors subpoenaed Twitter for several months of his tweets, which are no longer available online, to combat his argument that police appeared to lead the protest onto the bridge before turning around and arresting them for walking on the roadway.

Electronic privacy advocates worry a precedent could be set that would make it more difficult for social media users to challenge law enforcement's use of their online words against them.

Twitter and Harris have unsuccessfully fought the subpoena, which has been repeatedly upheld as lawful by Manhattan Criminal Court Judge Matthew Sciarrino. The San Francisco-based company finally surrendered the tweets earlier this month after Sciarrino threatened it with contempt and a hefty fine.

Sciarrino had agreed to seal the tweets until a state Supreme Court judge ruled on Harris' latest request for a stay of Sciarrino's order upholding the subpoena. The judge, Carol Huff, denied the request this week.

Martin Stolar, Harris' attorney, said he was "disappointed" but would continue to pursue other legal challenges.

Sciarrino is reviewing the tweets and will provide to prosecutors those that appear relevant to the criminal case.

Twitter still has an appeal of Sciarrino's order pending in an intermediate appellate court, scheduled to be heard in November.

Harris also has a separate civil action pending, claiming Sciarrino overstepped his authority; prosecutors have asked a court to dismiss that lawsuit as an improper attempt to circumvent the normal appellate procedure.

Harris' criminal trial is scheduled for December.

The case is People v. Harris, Criminal Court of the City of New York, No. 2011NY080152.

(Editing by Dan Grebler)?

(c) CopyrightThomson Reuters 2012. Check for restrictions at:?http://about.reuters.com/fulllegal.asp?

Source: http://www.nbcnews.com/technology/technolog/occupy-wall-street-protester-cant-keep-tweets-prosecutor-6150370

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Thursday, September 27, 2012

Construction approved for Ithaca community complex | The Ithacan

Ithaca Estates Realty, a local rental company, has received final approval from the Town of Ithaca Planning Board to begin construction of a community shopping complex building project near the Ithaca College Circle Apartments this fall.

Evan Monkemeyer, real estate broker and community builder for Ithaca Estates Realty LLC, said the complex will house a fitness center, a bank and an Ithaca Bakery restaurant.

Monkemeyer said that he hopes a restaurant will rent one of the retail property and can use the over eighty outdoor dining spaces he has planned.

The project had been set to break ground in the summer of 2011, but it will now most likely start construction in early October. The complex should be ready to open by next fall, as long as they are able to obtain a building permit.

The project has been considered since around 2005, Monkemeyer said. The complex, which is set to hold both residential and commercial spaces, will be located on the corner of East King Road and 96B. There are also plans for a paved walkway that goes from the back of the building to the Circle Apartments.

College Crossings Ithaca
Shawn Steiner/The IthacanCollege Crossings, a community complex on East King Road and 96B, will include six commercial spaces and two four-or-five-person apartments.

Monkemeyer said financial reasons and difficulty obtaining bank loans forced him to postpone the project, which he estimates will cost him close to $2 million. The original design for the project was estimated to cost more, but Monkemeyer said he decided to contract it himself to cut costs. Monkemeyer said he doesn?t have projections about project gains yet.

In the original College Crossings design, Monkemeyer said, the building was supposed to be a commercial building with offices on top and businesses on the bottom. However, in the current design, the building, which will be more than 19,000 square feet, will have six commercial spaces on the main floor and a space for two four-or-five-person apartments. This makes it a mixed-use commercial and residential building.

Sue Ritter, director of planning for the Town of Ithaca, said the project seems to be on track.

?What?s required is getting site plan approval and special permits from the planning board to be able to have this mixed-use building,? Ritter said. ?The next step really is for them to come to the town with a building permit.?

One feature of the project that the Town of Ithaca planning board liked was the plan to add a paved walkway from the back side of the location to the college, Monkemeyer said. He also said the walkway will? begin at the College Crossings parking
lot and will? to the Circle Apartments, which will make it easier for students to commute to downtown.

?It?ll give you pedestrian access from East King Road, in the Town of Ithaca, all the way to downtown,? Monkemeyer said. ?It will be blacktop and smooth, so you can bicycle, skateboard or jog.?

Junior Ian Vitkus, a resident of the Circle Apartments, said he thinks the project has potential to be useful to the college community.

?It could be a place to get stuff that?s actually close to campus that you don?t have to drive to,? Vitkus said. ?Underclassmen don?t have to rely on the buses.?

Monkemeyer said he hopes the project will benefit the South Hill community. He said he hopes to turn it into a more popular destination.

?For the size of the project, I think it?s going to be Collegetown for South Hill,? Monkemeyer said. ?It?s not going to be College Avenue or Dryden Road, not with six story high-rises. This is going to be a suburban look, a suburban feel, and it?s going to be a landmark building.?

Source: http://theithacan.org/25321

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Considering the Right Motor Boats for Sale

Nowadays, you can find motor boats for sale everywhere. You can find them in almost every local store in your area. In addition, you can find them in online stores in the internet if you do not want to go directly to the showroom. In the internet, you can browse any kinds of boats that you want to buy. You can always check the price and other things beforehand based on the types of boat that you want to procure. There are three kinds of boat that you can choose in local and online boat stores. They are new boats, used boats and luxury yacht.

New boats are the ones that are recently produced by the manufacturers. They are equipped with the newest features and technology that are invented recently. The boats are usually recommended by the sellers due to the newest features, which are comfortable and nice. It rarely happens for new boats to be sold in wholesale ways but there is still a possibility that new motor boats for sale will occur. Of course, there are reasons behind this. One of the reasons is to promote the new boats that a certain company produces. It can be used as an effective way to boost the selling points.

Used boats are boats that have been bought by other people beforehand. Some people may get bored with the boats that they own, and then they decide to sell them and buy a new one. You can find them in some local and online boat stores with a wide range of prices. Buying used boats has many advantages. One of them is that it saves a lot of money. Used boats cost much cheaper than the new ones. Besides, used motor boats for sale can often be found in the stores, both local and online stores.

Luxury yachts are boats that are made for rich and ?lite people. Since this kind of boat costs so much money, only hardcore boat enthusiasts with money can afford it. There are some ways to get this kind of boat. One of them is by hiring a broker. A broker can help you deal with financing, deal brokering, inspection arrangement, title clearing and procuring, docking space and yacht services for the luxury yacht you want to purchase. Moreover, there is also a place where you can have the service of a broker that will help you purchasing the luxury yachts you always dream of. This place is called Yachtcouncil. This place will also help you find a place for luxury motor boats for sale. However, it is rare for luxurious motor boats will be sold for sale, but there are some sales for luxury yachts that you can enjoy.


Looking for yacht to buy is a delicate process. There are some aspects that you should consider before purchasing the yachts you want. The first thing to consider is the type of the yacht you need. The one that is recommended is the hull type. However, there are two types of hull type: mono-hull and multihull. You can pick either one with the facilities and the risks that are offered by each of them. Nevertheless, this type of boat is the best type of boat nowadays, so you will find many more benefits than the risks. The second thing to concern about is the material used to produce the yachts you want to buy. The most common material that is used is GRP or Glass Reinforced Plastic. This material is well known for its lightness, durability, and cheapness. These are some characteristics you should really pay attention to when buying luxury yachts or motor boats for sale.

Source: http://www.artipot.com/articles/1386625/considering-the-right-motor-boats-for-sale.htm

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Dow plummets 100 points in stock sell-off

Stocks dropped after?Charles Plosser, president of the Fed's Philadelphia branch, told an audience Tuesday that the Fed's effort to support the economy would likely fall short of its goals.

By Matthew Craft,?AP Business Writer / September 25, 2012

Philadelphia Federal Reserve President Charles Plosser speaks at an Economics21 event in New York in this March 2011 file photo. Plosser said he doubted the bank's effort to boost economic growth would work, sending stocks tumbling Tuesday.

Brendan McDermid/Reuters/File

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A quiet day on?Wall?Street?turned into the worst sell-off in three months after a Federal Reserve official said he doubted the bank's effort to boost economic growth would work.

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Charles Plosser, president of the Fed's Philadelphia branch, told an audience Tuesday that the Fed's effort to support the economy would likely fall short of its goals. And if the Fed looks ineffective, it could undermine future Fed action.

The speech probably startled some investors who had faith in the Fed's latest plan, said Jack Ablin, chief investment officer Harris Private Bank. The plan includes buying $40 billion in mortgage bonds each month until the economy improves.

"So many investors have bought into the illusion," he said. "And it was like Plosser pulled up the curtain on the Wizard of Oz."

The Standard & Poor's 500 index lost 15.30 points, its fourth straight decline, to close at 1,441.59. The 1.05 percent drop was the worst for the S&P since June 25.

The Dow Jones industrial average lost 101.37 points to close at 13,457.55. Caterpillar tugged the Dow down, losing 4 percent. The world's largest maker of bulldozers and other heavy equipment said late Monday that slower economic growth around the world dampened its earnings forecast. Its stock sank $3.86 to $87.01.

A batch of encouraging economic reports gave the stock market a nudge in morning trading. House prices rose in major cities for a third straight month, and a gauge of consumer confidence came in surprisingly high.

More surprising than those two economic reports was the Richmond Federal Reserve's strong reading on regional manufacturing, a recent trouble spot, said Phil Orlando, chief equity strategist at Federated Investors.

"Look at that. There were three data points on the economy and we crushed them," said Phil Orlando, chief equity strategist at Federated Investors.

But sagging profits could drag on the stock market in the coming weeks, Orlando said. Caterpillar joined a growing collection of companies have lowered their earnings forecasts. FedEx, a bellwether of world trade, said that shipping has sunk to recession-like levels. Railroad giant Norfolk Southern has also warned that falling shipments and sinking coal prices will likely drag down its earnings.

Wall?Street?analysts now estimate that corporate profits will sink this quarter from a year earlier. That would be the first such drop in three years.

The Nasdaq composite index dropped 43.05 points to 3,117.73. Google's stock touched an all-time high in early trading, clearing $764, but closed the trading day at $749.16.

Apple, the largest public company in the world, lost $17.25, or 2.5 percent, to close at $673.54. It has lost more than $26 in two days. Apple is the biggest component in the S&P but is not included in the Dow, helping explain why the S&P suffered a greater percentage decline than the Dow's 0.8 percent.

The closely watched Standard & Poor's/Case Shiller index of national house prices increased 1.2 percent in July compared with the same month in 2011. Prices rose from the previous month in all 20 major cities tracked by the report for the third month in a row.

The Conference Board said its gauge of consumer confidence shot to a seven-month high in September, trumping forecasts by a large margin. People surveyed said they were more optimistic about the job market.

The Federal Reserve's manufacturing index, which surveys companies in the central Atlantic region, increased after shrinking for three months as businesses turned more optimistic. Companies said they anticipate more orders and shipments even as employment dips. The index turned positive in September after a negative reading in August.

All three major stock indexes have surged or more this month, buoyed by a new plan from the Federal Reserve to support the U.S. economy. Both the Dow and the S&P 500, the benchmark for most stock funds, have gained more than 3 percent.

Treasury prices rose as traders shifted money into safe assets. The 10-year Treasury yield, the benchmark for mortgages and other loans, dipped to 1.67 percent, down from 1.71 percent late Monday.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/8O67J15PMlA/Dow-plummets-100-points-in-stock-sell-off

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Increase Web Traffic Through SEO Internet Marketing ? Internet ...

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Increase Web Traffic Through SEO Internet Marketing ? Internet Marketing Blog Tools

If you want to find out tips on how to do SEO Internet marketing so that you can use its full potential, then read this article. This will give you some insights on how to drive maximum traffic to your website by utilizing Internet marketing blog tools.

It is the main aim of SEO marketing to increase the traffic in one?s website. Web traffic is very important when you place your products and services over the Internet for advertising and promotion. An online entrepreneur will never sell and earn more profits without considering the increase in web traffic. It is customary in online marketing to create your own website so that you can have a place where to promote the products or the services that the business is offering.

However, the promotion and advertising should not stop there. It should also be part of the scheme to advertise the website itself so that it will gain popularity on the Internet. One way to do is by submitting the link of your website to several bookmarking sites. By doing this, you can be assured that, in one way or another, you gain the web traffic that you have always been wanting to have.

This is what we call SEO Internet marketing ? ensuring that your website is getting the high ranks in major search engines like Google and Yahoo. Once your website is able to achieve, you can expert better visibility on the Internet which is prerequisite earning more income from sales and profits.

Another effective means for SEO marketing is using Internet marketing blog tools. When you use this type of scheme you need to be ready with your articles. You can start by searching for blogsites that have topics related to your business niche. Once you have already registered to a number of these sites, then its time to conceptualize some topics for writing.

Make sure that the topics for your blog posts are very relevant to your business. Write them in such a way that it is in good quality. This is because most of the search engine operators or managers will base its rankings for your website on the contents of the articles. So make the contents very informative and substantial. Plus, the articles should not contain inconsistencies in grammar and spelling.

When you submit these articles in the blogsites in your list, make sure to include tags and keywords. These two elements in Internet marketing are very important because these can drive so much traffic t your website like crazy. Note that when people search for information on the Internet, they will always use tags and keywords in search engines.

The main thing that you should not neglect are backlinks. Post your articles in blogsites with the backlinks of your website. Select a keyword from your article and make it as anchor text for your backlinks. Without this backlinks there will be no way for the readers to visit your website which means less traffic. This is why every article posted in the blogsites should have these links. It is even recommended that you submit more articles in more sites. By doing this you will more better chances of having an increase web traffic that will lead to more profits. Blogging is only one tool that you can use for SEO Internet marketing.

Source: http://internet-marketing-guide.org/increase-web-traffic-through-seo-internet-marketing-internet-marketing-blog-tools/

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how to make extra money online ? 60 seconds | Arquitectosfca.org

The Net supplies a large collection of earning chances for men and women approximately the earth. No matter whether you are a ten yr old lady or a 70 yr old gentleman, you can without difficulty locate techniques to bring in hard earned cash on line. There are various chances to bring in hard earned cash in different fields, and a particular has to locate the correct way as for each his education, go through, knowledge, expertise-set and fascination. Here we are likely to examine about the ten most beneficial techniques to make hard earned cash on line.

1. Make Money Online
Infolinks ? If you have a web site or blog page that has fantastic written content on any certain subject then you can get your website or blog page registered with Infolinks. They supply in-text promotion to their members. You must have noticed written content text backlinks to distinct websites in distinct post directories they are next to nothing but in-text promotion. It is a terrific source of earning hard earned cash on line.

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These are some of the legit techniques to bring in on line. So, if you happen to be thinking about how to make hard earned cash on line, you can acquire your time and Google some zones of fascination and then start off earning hard earned cash within a small time. With far more and far more on line chances coming up on a day-to-day foundation, you can be sure that the foreseeable future is vibrant certainly.

Source: http://www.arquitectosfca.org/how-to-make-extra-money-online-60-seconds/

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My Week With PT Anderson, Day Six: The Master

Jeff ends his journey with Anderson's latest, a character drama revolving around a cult.

86%

After years of waiting (and rumors about its storyline supposedly being inspired by the life and times of Scientology founder L. Ron Hubbard) Paul Thomas Anderson's sixth full-length film, The Master, is finally in wide release -- bringing us to the conclusion of our Anderson watching series with one of the more widely anticipated (and hotly debated) movies of the year. How does it fit into his Oscar-nominated filmography? Let's discuss.

Anderson has said he was inspired by a quote pointing out that people often gravitate to spiritual movements during postwar periods, and in very general surface terms, that's what The Master is about -- if you've read up on your Scientology, you can draw certain parallels between Hubbard and the movie's cult-shepherding Master, Lancaster Dodd (Philip Seymour Hoffman), but if you go in not knowing your Scientologists from your Moonies, you should still be able to recognize the pattern: When a society goes from a wartime environment where everything is at stake to the numbing conformity of peacetime, people tend to go searching for something to latch onto.

People like Freddie Quell (Joaquin Phoenix), the Pacific-stationed World War II soldier we meet in the movie's opening frames. From our first glimpse of Freddie, we can tell he's a troubled individual, and we survey the damage in a series of largely dialogue-free shots that paw over familiar ground for Anderson: Man using nature; man using man; man struggling gracelessly with sex, lust, and loneliness. We quickly learn that Freddie has a thirst for peculiar cocktails (in the first of many wince-inducing scenes, he celebrates the announcement of V-J Day by siphoning straight torpedo fuel for some improvised moonshine), as well as enough emotional turmoil to earn a PTSD diagnosis.

If you've read anything about The Master, you know this is a role Phoenix absolutely crushed, and it's his prowling, jittery energy that really drives the action in the movie. He's a feral presence, particularly in the opening act -- he struggles to put on a happy face during a session with a VA psychologist, makes a vain, half-hearted attempt to fit into postwar society with a job as a department store photographer, and manages to make a mess out of a stint as a migrant farmworker, all the while giving off the raw, dark energy of a man who's barely walking the line between volcanic self-loathing and animal self-preservation. It's always fun to try and spot the seams when an actor tries to disappear into physical tics as pronounced as Phoenix's here, but he leaves nothing behind.

Anderson has also said that portions of The Master's screenplay were taken from unused scenes for There Will Be Blood, and that makes sense; you can detect a certain whiff of that movie's dynamic here, once Freddie crosses paths with Dodd. But unlike Blood's Daniel Plainview and Eli Sunday, Freddie and Dodd aren't opposites, or even really enemies; although it's still very much a struggle for power, their relationship is a lot more complicated, with enough love and heartbreak for a dozen romantic dramas.

Dodd initially appears to be the one in command -- and the key to a safe, happy future for our anguished drifter -- but after our first few moments in his presence, we start getting hints that behind his self-made sect's glowing fa?ade (and his own charismatic persona) lurks a different kind of darkness, as well as another power struggle between the members of Dodd's family (led by his quietly terrifying wife Peggy, played to steely perfection by Amy Adams). Fittingly for a guy with a fondness for borderline poisonous hooch, Freddie proves a volatile addition to the mix -- not only because his presence aggravates the tension, but because he gives off an unpredictably violent energy that's always threatening to erupt.

It's a story ripe with potential, and one that finds Anderson delivering some of his most beautifully composed shots. From a directorial standpoint, The Master really is the work of a master; he's firmly in control here, spooning out a visual feast that includes a number of familiar ingredients (he still likes framing shots with missing information, and he's really in love with putting his characters in the middle of hallways, ramps, doorways, trails -- you name it) while markedly increasing his use of close-ups, as well as the sense of detached stasis that pervaded There Will Be Blood. Looming over it all, and adding to the general sense of unease, is Blood composer Jonny Greenwood's score, which tells its own story with sweeping, sometimes discordant movements.

As with any Anderson picture, the question of What It All Means looms large over every frame, and The Master has already generated plenty of heated discussion. There are critics who see it as a grand statement on the search for meaning in modern consumer-driven American culture, there are those who interpret it as a homoerotic love story, and there are those who think it's all just a bunch of thinly scripted hooey. As Roger Ebert put it, "The Master is fabulously well-acted and crafted, but when I reach for it, my hand closes on air."

Personally, I started off in the first camp, but as the movie wore on, I found myself edging into the third. It's certainly Anderson's chilliest movie; it sweeps you up while you're watching, but it always keeps you at a distance, so while you're trying to untangle its themes later on -- themes that Anderson seems to make a point out of refusing to fully address -- it's easy to wonder what the point of the whole thing really is. The Master lingers, but not in a particularly enjoyable way.

It can be argued that it's unfair to expect high art from a film, and Anderson himself insists that his movies are the stories of people, not themes or ideas -- which is certainly more than fair. But with The Master, Anderson the screenwriter fails Anderson the director -- the characters are just sketches and their actions are inscrutable, so if they aren't being used to tell a broader story, then they don't really serve any purpose at all. Sometimes it feels like we're seeing half a movie; the effect is unpleasant, unmooring.

But on the other hand, it's hard to look at The Master in the context of modern American cinema and come away judging it too harshly. As frustrating as its tendency to elide can be, it's still a film that refuses to talk down to its audience. (It may accomplish that by refusing to speak to its audience at all, but still.) It's beautiful in an era when true cinematography is hard to find, it's deeply ambiguous in a studio system that prizes the lowest common denominator, and it contains some of the most powerful acting you're liable to see all year. If it's a failure for Anderson, maybe it's still a victory for filmgoers who want to be treated like adults -- who want to consider and discuss what they've seen over a period of days and weeks, instead of forgetting the whole thing before they're even out of the theater parking lot.

On those terms, I appreciated The Master, and I'm glad Anderson is out there fighting the good fight, proving mainstream audiences still want something more than mindless entertainment -- but I wouldn't watch it again, despite the prevailing notion that it's a film that needs to be seen two or three times to truly appreciate. At one point in the movie, there's an exchange that goes as follows:

"I don't understand it."

"I don't either -- that's why we're here."

That about sums up the whole experience for me -- and fittingly, as I walked out of the theater, Rick Astley's "Never Gonna Give You Up" was playing on the PA system. I had to laugh; for film fans, The Master might be the biggest Rickroll of the year.


See more:

Monday: Hard Eight

Tuesday: Boogie Nights

Wednesday: Magnolia

Thursday: Punch-Drunk Love

Friday: There Will Be Blood

Monday: The Master

Source: http://www.rottentomatoes.com/m/1925949/news/1925949/

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Wednesday, September 26, 2012

Tesla Motors rolling out ultra-fast Supercharger electric car charging stations

Mitt Romney's recent slide in several polls, including those in the battleground states of Ohio, Virginia and Florida, is troubling enough for the GOP. But, now the Republican nominee appears to be trailing President Barack Obama among a traditionally conservative constituency: NASCAR fans. Obama leads Romney 49 to 42 percent among NASCAR enthusiasts, according to [...]

Source: http://news.yahoo.com/blogs/technology-blog/tesla-motors-rolling-ultra-fast-supercharger-electric-car-180042589.html

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Saturday, September 22, 2012

Universal wins EU approval for EMI buy, must sell assets

BRUSSELS (Reuters) - Vivendi's Universal Music Group clinched EU regulatory approval on Friday to buy EMI's recorded music unit for $1.9 billion after agreeing to sell record labels that bring in nearly a third of the British company's revenues.

The combined group, which would include a vast library of current top-selling and legendary names including Jay-Z, Kanye West, Katy Perry and Pink Floyd, proposed the asset sales after EU regulators raised concerns over the potential market power of the combined group.

Universal said the assets to be sold amounted to 30 percent of EMI's group revenues or roughly 10 percent of sales for the combined group.

It will sell Parlophone, one of EMI's most prized labels with star acts such as Coldplay and Queen. The Beatles will not be included in the disposals.

Also on the block will be the Mute, Ensign and Chrysalis labels, EMI Classics, Virgin Classics, EMI's share of the "NOW! That's what I call music" compilation business, and EMI units in France, Spain, Belgium, Denmark, the Czech Republic, Poland, Portugal, Sweden and Norway.

Universal will also sell its brands Sanctuary, Co-Op Music Ltd, King Island Roxystar, MPS Records, its share in Jazzland, and its Greek unit.

Reuters reported on September 3 that the EU watchdog would clear the takeover after Universal offered to sell global rights to some of EMI's record labels and catalogues.

Industry experts said the value of the package could be as high as $750 million.

The European Commission said buyers must be active record firms or those with a proven track record in the music industry, ensuring that there would be a strong rival to Universal.

Potential buyers include Warner Music Group, BMG - which is the music publishing joint venture between German media group Bertelsmann and private equity group KKR, as well as Virgin Records founder Richard Branson and Sony Music.

"The very significant commitments proposed by Universal will ensure that competition in the music industry is preserved and that European consumers continue to enjoy all its benefits," EU Competition Commissioner Joaquin Almunia said in a statement.

EMI's seller, Citigroup Inc, acquired EMI from buyout group Terra Firma when it defaulted on loans owed to the investment bank. The proposed deal will cement Universal's No. 1 position in the European music industry.

(Reporting by Foo Yun Chee; editing by Rex Merrifield)

Source: http://news.yahoo.com/universal-wins-eu-approval-emi-buy-must-sell-094608856--sector.html

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Video: Salman Rushdie talks new book, furor over anti-Muslim film (cbsnews)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS and RSS Feed via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/250243273?client_source=feed&format=rss

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Video: Cold murder case reopened after 42 years

Sorry, Readability was unable to parse this page for content.

Source: http://www.msnbc.msn.com/id/21134540/vp/49129851#49129851

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Friday, September 21, 2012

Amazing Benefits of The Banana

Banana-a perfect food

Bananas are nutritious and tasty and have many vitamins: is an excellent source of potassium and fiber especially vitamin B (owns 9% of vitamin B, 37% of vitamin B6 and 7% of its vitamin B9) . This quickly removes toxins from the body, strengthens the immune system and the vitamin C present in banana helps produce collagen.
Bananas are an excellent source of phosphorus, calcium, potassium, niacin, vitamin E, carbohydrates, proteins. With so many vitamins I can say that are simply amazing. However, that is not all. They say that it can regulate blood pressure and protect the kidneys. Carbohydrates are healthier than those found in bread, rice, peas, etc... It is said that those who regularly consume bananas are protected from leukemia. Also, very good winter when lacking vitamins and minerals from fruits and vegetables.
Two bananas a day provides sufficient potassium. It is very important because potassium keeps the blood pressure under control, prevents heart diseases. Bananas don't have a high glycemic index, have a lower cholesterol level and reduce the risk of constipation. Other benefits of banana: energy because of carbohydrates, fight against the hangover, heal stomach burns, heal mosquito bites, help calm the nervous system, removes warts, remove coughs. Amazing!
Some studies have shown that bananas improve eyesight, like carrots. Frequent consumption of this fruit strengthens bones and helps the body absorb calcium better.It has a high content of provitamin A that protects against chronic diseases, cancer, diabetes.

How to keep bananas fresh

It was found a product that makes bananas stay fresh for longer time. Substance kills bacteria that cause spoilage and limit the absorption of oxygen in the atmosphere. This product is tasteless, non-toxic and is applied as a spray on a banana peel. It is known that bananas are well preserved during transport. When they reach the buyer it may change in a very short time. This spray may be the solution.

Bananas and our beauty

Bananas, besides the fact that they have many vitamins and minerals, whiten your teeth. For teeth bleaching, use the inside of the shell. All you have to do is to rub the shell on your tooth few minutes. Banana, if turned into a paste and is applied to the surface of the teeth lead to visible results in one week.
Did you know that bananas prevent hair loss? There are some recipes with bananas that regenerate hair, especially if it is dry or oily. It can be used as a conditioner or moisturizer with banana mask. Another important thing is that banana treat acne and remove signs of aging.

Author's Bio:?

Richie Dragos has been writing articles online for nearly 2 years now. Not only does this author specializes in health, diet, fitness and dental care, you can also check out his latest website on bleaching kits and other tips and advices related to teeth whitening and dental care like brushing your teeth,receding gums, fluoride toothpastes, etc.

Source: http://www.selfgrowth.com/articles/amazing-benefits-of-the-banana

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MLSU: International Seminar on Global Business Research

mlsu-conference1

The inaugural ceremony of the International Conference on Global Business Research took place today at 11 am in the Mohan Lal Sukhadia University Auditorium organized by the University College of Commerce and Management Studies and hosted by Master Human Resource Management and Banking & Insurance Program.

Gajendra Singh Shaktawat, Parliamentary Secretary was the chief guest of the occasion and inaugurated the conference by lighting up the lamp & garlanding the portrait of Goddess Saraswati along with Prof. I.V. Trivedi, Vice Chancellor MLSU.

mlsu-conference

Director of the conference and Dean Commerce College, Dariyav Singh Chundawat delivered the welcome speech and expressed his gratitude to all the guests present.

?University will keep organizing these type of seminars in order to promote academic contributions by the students?, said I.V. Trivedi.

mlsu-conference3

Key note speaker on the occasion was Professor Som Deo, Dean, University College of Commerce, University of Rajasthan. He said, ?Global Business Research is such an important topic; if you are interested in this topic, you will love it for sure. The global scenario is changing and business opportunities are being generated all over the world, hence, global research is very important?.

Later, Prof KC Sodani declared the names of the best paper awardees and Prof. I.V. Trivedi presented the awards.

mlsu-conference2

Professor Trivedi and Professor DS Chundawat released the souvenir along with other guests present on the occasion.

Prof. PK Singh delivered the vote of thanks in the inaugural ceremony.


Source: http://www.udaipurtimes.com/mlsu-international-seminar-on-global-business-research/

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Thursday, September 20, 2012

Polls: Making Gains On The Economy, Obama Leads In WI And VA, But CO Remains Close

With a strengthened position on the economy, President Barack Obama claims clear leads in two swing states, including in Republican vice presidential nominee Paul Ryan's native Wisconsin, while the race is tight in a western battleground, according to a new slate of polls released Wednesday.

The latest round of polls from Quinnipiac University, CBS News and the New York Times show Obama leading Mitt Romney among likely voters in Wisconsin (51 percent to 45 percent) and in Virginia (50 percent to 46 percent), while the president narrowly edges his GOP challenger in Colorado (48 percent to 47 percent).

Obama's lead in Wisconsin represents a bump for the Democratic ticket from a month ago, when the the previous Quinnipiac/CBS/NYT poll showed the president hanging on to a 2-point edge among likely voters in the state. Coinciding with Obama's expanded lead in the Badger State is a shift in voters' preference over which candidate is better-suited to preside over the economy. A month ago, 49 percent of Wisconsin voters said Romney would do a better job on the economy, compared with 43 percent who preferred Obama on the issue.

Today, Wisconsin voters give Obama the edge on the all-important issue, 49 percent to 46 percent -- striking a blow to Ryan, whose economic pitch has centered around hardships in his hometown of Janesville, Wis.

The president also claims an advantage on the economy in Virginia, 49 percent to 47 percent, reversing a 2-point Romney lead held in the Commonwealth a month ago. And while Romney is slightly preferred by Colorado voters to handle the economy, 48 percent to 47 percent, it's a steep drop for the Republican nominee from a month ago. In August, 51 percent of Colorado voters gave Romney the nod on the economy, outpacing the president by 10 points on the issue.

These state-level gains by Obama on what had been a consistent strength for Romney dovetail with recent national polls, which have likewise shown the president cutting into his opponent's advantage on the economy since the conclusion of the Democratic National Convention.

Wednesday's polls also show voters in all three swing states believe Obama would do a better job than Romney handling an international crisis and national security, areas with added weight in light of the ongoing tension in the Middle East and North Africa.

The PollTracker Average currently shows Wisconsin and Virginia slightly favoring Obama, while Colorado is in tossup territory.

The swing state polls were conducted by Quinnipiac University Sept. 11-17 using live telephone interviews of 1,497 likely voters in Colorado, 1,474 likely voters in Virginia and 1,485 likely voters in Wisconsin. Each sample has a margin of error of three percentage points.

(Photo Credit: Brett Marty Photography)

Source: http://news.yahoo.com/polls-making-gains-economy-obama-leads-wi-va-123524291--politics.html

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Dell's Latitude 10 tablet and dock, OptiPlex 9010 AIO, Latitude 6430u laptop arrive to tempt business pros

Dell's Latitude 10 tablet and dock, OptiPlex 9010 AIO and Latitude 6430u laptop arrive to tempt business pros

Windows 8 is coming folks, and so is an onslaught of new machines featuring Microsoft's something-for-everyone OS. Dell already showed us some of its fresh consumer Win8 hardware back at IFA 2012, and now it's the enterprise's turn to shine. First up is the Latitude 10 tablet, which packs an Intel Atom SoC, a 10.1-inch IPS 1366 x 768 LCD display covered in Gorilla Glass, 8-megapixel primary camera plus an HD front-facing shooter. It's got 2GB of RAM and up to 128GB of eMMC NAND storage, plus an SD card slot should the integrated storage prove insufficient. Connectivity comes via one full-size USB 2.0 port, a microUSB charging socket, mini-HDMI, a headphone/microphone combo jack, proprietary docking port and a micro-SIM slot for WWAN use. The Latitude 10 packs up to a 60Wh battery, which isn't remarkable in and of itself, but the fact that it's removable is. That means road warriors can travel with a spare cell or two to keep their slate in the juice no matter how long they work on it. While the swappable battery can keep the 10 from being tethered to an outlet, the dock Dell built for it ensures it'll have a stylish place to rest when it is. The dock expands the slate's connectivity with four USB 2.0 sockets, Gigabit Ethernet, HDMI and audio output.

Next is the Optiplex 9010 all-in-one desktop we saw earlier this year. It still has the same 23-inch, 1920 x 1080 panel on the front and vPro-equipped Ivy Bridge silicon lurking beneath -- the only change is the upgrade from Windows 7 to Windows 8. The Latitude 6430u is an addition to Dell's venerable business laptop line, and is the first to bear the Ultrabook moniker. It's generous to label the 6430u as such, as it's .82 inches thick and weighs 3.7 lbs, but it's still a fairly thin and light laptop -- plus it has the same solid magnesium chassis construction as its Latitude brethren. The 6430u crams a 14-inch, 1366 x 768 matte display into its 13.3-inch chassis, and users have the option of Ivy Bridge Core i3, i5 and i7 silicon with vPro, up to 8GB of RAM and up to 256GB worth of solid state storage. Naturally, there's 802.11 b/g/n WiFi, Bluetooth and mobile broadband available for wireless connectivity. Unfortunately, we can't tell you how much Dell's new business computers will cost, but we do know that they'll be available when Windows 8 is, which is to say late October.

Continue reading Dell's Latitude 10 tablet and dock, OptiPlex 9010 AIO, Latitude 6430u laptop arrive to tempt business pros

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